Compile Data Set for Download or QSAR
Found 95 from Westfalische Wilhelms-Universitat
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50377913(HYPERFORIN)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Binding affinity to pregnane receptor in human hepatocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50129952(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  372nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50318294(CHEMBL1098724 | miquelianin)copy SMILEScopy InChI
Affinity DataKi:  4.06E+3nMAssay Description:Binding affinity to adrenergic alpha2c receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataKi:  7.85E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50217942(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chr...)copy SMILEScopy InChI
Affinity DataKi:  9.34E+3nMAssay Description:Binding affinity to adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50217942(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chr...)copy SMILEScopy InChI
Affinity DataKi:  9.64E+3nMAssay Description:Binding affinity to adrenergic alpha2c receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258696((S)-1-[4-(Allyloxy)benzyl]-5-[1-(2-methoxymethylpy...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258337((S)-1-(4-Fluoro-3-hydroxybutyl)-5-[1-(2-methoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258698((S)-1-[4-(3-Fluoro-2-hydroxypropoxy)benzyl]-5-[1-(...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258694((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258380((S)-1-[4-(1-Fluoro-2-hydroxyethyl)benzyl]-5-[1-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258697((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258694((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258696((S)-1-[4-(Allyloxy)benzyl]-5-[1-(2-methoxymethylpy...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258699((S)-1-[(S)-2,3-Dihydroxypropyl]-5-[1-(2-methoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10318((S)-5-{1-[2-(Phenoxymethyl)pyrrolidinyl]sulfonyl}i...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258697((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258335((S)-1-[(S)-3-Fluoro-2-hydroxypropyl]-5-[1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258378((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258667((S)-1-Allyl-5-[1-(2-methoxymethylpyrrolidinyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258667((S)-1-Allyl-5-[1-(2-methoxymethylpyrrolidinyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258668((S)-1-(But-3-enyl)-5-[1-(2-methoxymethylpyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258699((S)-1-[(S)-2,3-Dihydroxypropyl]-5-[1-(2-methoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258668((S)-1-(But-3-enyl)-5-[1-(2-methoxymethylpyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258378((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258336((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258669((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50259862(13,II8-biapigenin | 3,8''-biapigenin | CHEMBL51525...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258380((S)-1-[4-(1-Fluoro-2-hydroxyethyl)benzyl]-5-[1-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258337((S)-1-(4-Fluoro-3-hydroxybutyl)-5-[1-(2-methoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258669((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258698((S)-1-[4-(3-Fluoro-2-hydroxypropoxy)benzyl]-5-[1-(...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258336((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-3(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)copy SMILEScopy InChI
Affinity DataIC50: 275nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10318((S)-5-{1-[2-(Phenoxymethyl)pyrrolidinyl]sulfonyl}i...)copy SMILEScopy InChI
Affinity DataIC50: 294nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99642PubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
TargetCaspase-7(Homo sapiens (Human))
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258335((S)-1-[(S)-3-Fluoro-2-hydroxypropyl]-5-[1-(2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 349nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN163DPubMed
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